葛根素通过调控活性氧对缺氧诱导的PASMCs增殖的影响(4)
缺氧组的Cyclin A明显上调,与缺氧组对比,Pue组Cyclin A明显下调(P<0.01),Pue+Rote-
1.常氧组;2.常氧+Pue组;3.缺氧组;4.缺氧+Pue组。
图6 DCFH-DA探针检测PASMCs中ROS的表达(A)及Western blot法检测Pue对PASMCs中HIF-1α表达的影响(B)(±s,n=6)
Fig.6 Effect of Pue on ROS expression of PASMCs detected by method DCFH-DA(A) and the effect of Pue on HIF-1α expression of PASMCs detected by Western blot(±s,n=6)
1.常氧组;2.缺氧组;3.缺氧+Pue组;4.缺氧+Pue+Rotenone组;5.缺氧+Rotenone组(图8,9同)。
图7 Pue和Rotenone对PASMCs中HIF-1α表达的影响(±s,n=6)
Fig.7 Effect of Pue and Rotenone on HIF-1α expression of PASMCs(±s ......
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1.常氧组;2.常氧+Pue组;3.缺氧组;4.缺氧+Pue组。
图6 DCFH-DA探针检测PASMCs中ROS的表达(A)及Western blot法检测Pue对PASMCs中HIF-1α表达的影响(B)(±s,n=6)
Fig.6 Effect of Pue on ROS expression of PASMCs detected by method DCFH-DA(A) and the effect of Pue on HIF-1α expression of PASMCs detected by Western blot(±s,n=6)
1.常氧组;2.缺氧组;3.缺氧+Pue组;4.缺氧+Pue+Rotenone组;5.缺氧+Rotenone组(图8,9同)。
图7 Pue和Rotenone对PASMCs中HIF-1α表达的影响(±s,n=6)
Fig.7 Effect of Pue and Rotenone on HIF-1α expression of PASMCs(±s ......
您现在查看是摘要页,全文长 4443 字符。